L-Thyroxine (T4) CAS NO.51-48-9

Description:

Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form.

The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevatedcholesterol levels) but was withdrawn due to cardiac side effects.

Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.

Many bodybuilders take thyroid hormone in hopes of increasing their metabolism and reducing their bodyfat percentage for a contest. It is good in theory and generally harmless over a short duration, but in order to lessen the likelihood of muscle catabolism, a blood test in conjunction with use is needed.

Applications:

T4 is PRO-hormone, which your body converts into T3 at necessary rate only and thus it could be considered as much milder and safer drug than T3.

T4 is the most often used medication for hypothyroid conditions. Most of the mainstream physicians and endocrinologist prescribe T4. Prescribing T4 makes establishing and maintaining a proper dosing easier, and it's a rare condition when your body cannot convert T4 to T3 at the cellular level.

However, when there is difficulty converting T4 to T3, either T3 must be added to the therapy schedule or Powdered Thyroid must be prescribed. Additionally, most alternative medicine thyroid doctors believe that the powdered is a more natural way to treat thyroid disease.

T4 is a once a day medication. Most people take it first thing in the morning on an empty stomach. There is an option to take it sublingually to get better absorption.

To do this, the T4 tablet can be placed under the tongue and allowed to dissolve and be absorbed at a slower pace. Sublingual absorption avoids complications with digestion.

Levothyroxine sodium is an excellent fat burner since your metabolism is greatly increased while being on it.You can afford to be a little sloppier on pre-contest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire.

One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH).

Levothyroxine is a synthetic (man-made) version of the principle thyroid hormone, thyroxine (T4) that is made and released by the thyroid gland. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects.

Dosage:

Users discovered T3 to be a better choice over T4 when using Thyroid drugs during Cyclic Ketogenic Diets.T4 must be used in much higher doses to be as effective as T3. Subjects found they needed to use a dosage of 300 mcg/day to achieve the same results as 25-100 mcg/day of T3 (Cytomel).